pH-sensitive microparticles for oral drug delivery based on alginate/oligochitosan/Eudragit® L100-55 “sandwich” polyelectrolyte complex

- Naproxen-loaded alginate-oligochitosan microparticles were reinforced with Eudragit® L100-55.
- High encapsulation efficiencies were achieved (>74.4%).
- pH-sensitivity was improved by oligochitosan-Eudragit® L100-55 ionic interactions.