Co-production of 3-hydroxypropionic acid and 1,3-propanediol by Klebseilla pneumoniae expressing aldH under microaerobic conditions

- Klebseilla pneumoniae expressing E. coli aldH was cultured under microaerobic conditions.
- Aeration enhanced 3-hydroxypropionate production but lowered 1,3-propanediol formation.
- The highest 3-hydroxypropionate was 48.9 g/L in 28 h at the aeration rate of 1.5 vvm.
- The specific formation rates of metabolites were compared.
- Carbon and redox balances were performed.