The catalytic activity enhancement and biodegradation potential of free laccase and novel sol-gel laccase in non-conventional solvents

► We successfully synthesized a novel sol-gel laccase (SOLAC). ► The catalytic activity of SOLAC in ionic liquids and organic solvents were improved. ► The SOLAC gave higher biodegradation rate in either aqueous or organic solvents. ► The pre-saturation of solvents with water was necessary to sustain oxidation. ► SOLAC with and without additives were fairly stable and can be reused many times.