کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
71053 | 48864 | 2007 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Enantioselective benzylic microbial hydroxylation of indan and tetralin
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موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
کاتالیزور
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Enantioselective benzylic microbial hydroxylation of indan and tetralin Enantioselective benzylic microbial hydroxylation of indan and tetralin](/preview/png/71053.png)
چکیده انگلیسی
A screening with 15 strains of bacteria and fungi targeted at the production of specific hydroxylated benzylic derivatives of indan 1 and tetralin 2 was carried out. Mortierella isabellina, Mortierella ramanniana and Beauveria bassiana were shown to mediate the respective conversions to 1-indanol (3) and 1-tetralol (4), the most satisfactory results being obtained with M. isabellina, which gave 78% conversion of 1 to (1R)-3 (64% yield, 86% ee) after a 2-day-incubation, and 52% conversion of 2 to (1R)-4 (38% yield, 92% ee) in a 4-day-incubation. Over-oxidation of alcohols 3 and 4 during the reactions resulted on the formation of 1-indanone and 2-tetralone, respectively.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Molecular Catalysis B: Enzymatic - Volume 46, Issues 1–4, 2 May 2007, Pages 37–42
Journal: Journal of Molecular Catalysis B: Enzymatic - Volume 46, Issues 1–4, 2 May 2007, Pages 37–42
نویسندگان
Renata P. Limberger, Cleber V. Ursini, Paulo J.S. Moran, J. Augusto R. Rodrigues,