کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7229826 | 1470929 | 2018 | 21 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Improving sensitivity of a miniaturized label-free electrochemical biosensor using zigzag electrodes
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
To meet the requirements of a PoC application and to improve the measurement sensitivity for detection purposes, a three-electrode configuration was miniaturized and fitted onto a biochip. Computer simulation of an electrolyte current density was used to investigate several potential effective possibilities. It was found that an electrolyte current density at an edge tip structure near the working electrode (WE) and counter electrode (CE) was higher than at other locations. A zigzag structure was then designed at the edge near the WE and CE positions. With this design, we can obtain a higher total electrolyte current. This newly-designed biochip was then used to measure the electrochemical feature. It was found that the measurement efficiency was also improved using this newly designed biochip.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biosensors and Bioelectronics - Volume 103, 30 April 2018, Pages 130-137
Journal: Biosensors and Bioelectronics - Volume 103, 30 April 2018, Pages 130-137
نویسندگان
Yi-Ching Kuo, Chih-Kung Lee, Chih-Ting Lin,