کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7234679 | 1470991 | 2013 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Development of pH-based ElecFET biosensors for lactate ion detection
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
In this work, we report on ElecFET (Electrochemical Field Effect Transistor) devices potentially of interest for the detection of different molecules in solution. ElecFET are electrochemical microsensors in liquid phase, based on two elements: (i) a pH-sensitive chemical field effect transistor (pH-ChemFET) and (ii) a metallic microelectrode deposited around the sensitive gate. The coexistence of these two elements combines (i) potentiometric and (ii) amperometric detection effects at the microscale. Design, fabrication and experimental validation of ElecFETs based on silicon and polymer micro-technologies, are reported. We first demonstrate the detection of hydrogen peroxide (H2O2) in solution, showing a sensitivity of 5Â mV/mM in the [10-100Â mM] concentration range. The ElecFET concept is then extended to the detection of glucose and lactate in the [1-30Â mM] and [1-6Â mM] concentration range respectively. The sensitivities are between 2-6Â mV/mM and 8-20Â mV/mM respectively.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biosensors and Bioelectronics - Volume 40, Issue 1, 15 February 2013, Pages 291-296
Journal: Biosensors and Bioelectronics - Volume 40, Issue 1, 15 February 2013, Pages 291-296
نویسندگان
A.K. Diallo, L. Djeghlaf, L. Mazenq, J. Launay, W. Sant, P. Temple-Boyer,