کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
73325 | 49055 | 2013 | 7 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Controlled release of ferulic acid from a hybrid hydrotalcite and its application as an antioxidant for human fibroblasts Controlled release of ferulic acid from a hybrid hydrotalcite and its application as an antioxidant for human fibroblasts](/preview/png/73325.png)
• Ferulic acid was intercalated in a zinc–aluminium layered double hydroxide.
• The ferulic acid is controlled released from HDL under a biological media.
• Released ferulic acid inhibits oxidation of human fibroblasts.
• Oxidation of human fibroblasts is prevented for long time because of the controlled releasing.
Ferulic acid anions were intercalated in a Zn–Al layered double hydroxide. The materials generated by this process were characterised structurally and tested in two important applications: as in vitro drug delivery agents in a system that mimics biological conditions, for which a mathematical model describing the drug delivery profile was created, and as antioxidants for human fibroblasts.
Released ferulic acid from a hybrid layered double hydroxide reduces significantly the reactive oxygen species in human fibroblasts. Inhibition of oxidation occurs for periods as long as 24 h.Figure optionsDownload as PowerPoint slide
Journal: Microporous and Mesoporous Materials - Volume 181, 15 November 2013, Pages 1–7