Quantitative solid phase microextraction - Gas chromatography mass spectrometry analysis of five megastigmatrienone isomers in aged wine

- The first SPME-GC-MS method was developed for simultaneous quantification of five megastigmatrienone isomers in wine.
- The method was completely validated for white and red wines.
- The five megastigmatrienone isomers were quantified in 65 wines.
- Megastigmatrienone concentration increase with wine age.
- Aging wine in oak barrels enrich wine in megastigmatrienone.