Nanostructured rough gold electrodes as platforms to enhance the sensitivity of electrochemical genosensors

- Nanostructured rough gold electrodes as general DNA biosensors platforms.
- Electrode nanopatterning was accomplished by repetitive square-wave perturbing potential.
- Hybridization was electrochemically monitored by using electrostatic or intercalative indicators.
- PCR amplified real samples can be detected without complicated sample treatment procedures.
- The genosensor exhibits a wide linear range, high sensitivity and remarkable long-term storage stability.