کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7585905 | 1492043 | 2018 | 42 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Bioaccessibility, cellular uptake and transport of luteins and assessment of their antioxidant activities
ترجمه فارسی عنوان
دسترسی بیولوژیکی، جذب سلولی و انتقال لوتئین و ارزیابی فعالیت های آنتی اکسیدانی آن است
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی
A rapid method for producing 9Z- and 13â²Z-isomers from all-E-lutein was developed using I-TiO2 as catalyst. In a simulated in vitro gastrointestinal digestion model, both trans-cis isomerization of all-E-lutein and cis-trans isomerization of Z-luteins occurred during the intestinal phase. The bioaccessibility of all isomers was between 14 and 23%, and it was higher for Z-luteins. In a Caco-2 cell monolayer model, all isomers were relatively stable during cellular uptake and transport across the membrane as no significant isomerization and degradation was detected, but all-E-lutein exhibited significantly higher cellular uptake and transport efficiencies. These results suggest that Z-luteins found in human plasma may likely be formed before intestinal absorption. 13â²Z-Lutein also exhibited highest antioxidant activity in FRAP, DPPH and ORAC-L assays, but no significant difference in cell-based antioxidant assay compared with other isomers. Future studies on the different antioxidant activities of cis isomers of lutein in vivo will provide further explanation.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Food Chemistry - Volume 249, 30 May 2018, Pages 66-76
Journal: Food Chemistry - Volume 249, 30 May 2018, Pages 66-76
نویسندگان
Cheng Yang, Maike Fischer, Chris Kirby, Ronghua Liu, Honghui Zhu, Hua Zhang, Yuhuan Chen, Yong Sun, Lianfu Zhang, Rong Tsao,