کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7595467 | 1492123 | 2015 | 11 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Antioxidant and cytoprotective properties of partridgeberry polyphenols
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کلمات کلیدی
Nrf2Quercetin (PubChem CID: 5280343)Vaccinium vitis-idaeaEpigallocatechin (PubChem CID: 72277)Phloretin (PubChem CID: 4788)(−)-Epicatechin (PubChem CID: 72276) - (-) - Epicatechin (PubChem CID: 72276)Antioxidant - آنتی اکسیدانFerulic acid (PubChem CID: 445858) - اسید فرولیک (PubChem CID: 445858)Caffeic acid (PubChem CID: 689043) - اسید کافئیک (PubChem CID: 689043)Chlorogenic acid (PubChem CID: 1794427) - اسید کلرژنیک (PubChem CID: 1794427)Fractionation - تقسیم بندیCytoprotection - حفاظت از سیتوFlavonoids - فلاونوئیدهاLingonberry - لنگنبریPolyphenol - پلی فنلCatechin (PubChem CID: 9064) - کاتچین (PubChem CID: 9064)
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Partridgeberry (Vaccinium vitis-idaea) is a polyphenol-rich berry of the Ericaceous family, grown in Newfoundland and Labrador province of Canada. The aims of this study were to identify extraction solvents for the maximum recovery of polyphenols, to establish fractionation technique for isolation of major sub-classes of polyphenols, and to evaluate antioxidant and cytoprotective properties of the partridgeberry polyphenol preparations. The acidified 70% acetone was identified as the ideal solvent for the maximum recovery of polyphenols from partridgeberry. Further, aqueous two-phase extraction, column chromatography and UPLC-MS/MS were employed to produce three partridgeberry polyphenol fractions, rich in either, anthocyanins, flavan-3-ols or flavonols. All the three PPF were potent antioxidants and displayed cytoprotective activity through the activation of nuclear factor erythroid 2-related factor 2 pathway, scavenging of reactive oxygen species, and inhibition of cellular death. The current study suggests that partridgeberry has numerous potential health implications in both prevention and amelioration of various diseases involving oxidative stress.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Food Chemistry - Volume 168, 1 February 2015, Pages 595-605
Journal: Food Chemistry - Volume 168, 1 February 2015, Pages 595-605
نویسندگان
Khushwant S. Bhullar, H.P. Vasantha Rupasinghe,