کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7599638 | 1492144 | 2014 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Cytotoxic effect against 3T3 fibroblasts cells of saffron floral bio-residues extracts
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
PBSHClTPCTACTFACrocus sativus L.3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazoliumbromide - 3- (4،5-Dimethylthiazol-2-yl) -2،5-diphenyltetrazoliumbromideMTT - MTTTrifluoroacetic acid - اسید Trifluoroacetichydrochloric acid - اسید هیدروکلریک یا اسید کلریدریک یا جوهر نمک Phenolic composition - ترکیب فنلCell viability - زنده ماندن سلولPhosphate buffered saline - فسفات بافر شورTotal phenolic content - محتوای فنلی کلtotal anthocyanin content - مقدار کل آنتوسیانینKaempferol - کائمفرول
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله

چکیده انگلیسی
For every kilogram of saffron spice produced, about 63 kg of floral bio-residues (FB) (tepals, stamens and styles) are thrown away. Extracts of these bio-residues in water (W1), water:HCl (100:1, v/v) (W2), ethanol (E3), ethanol:HCl (100:1, v/v) (E4), dichloromethane (D5) and hexane (H6) were prepared. Their composition in flavonols and anthocyanins, and their effect on cell viability were determined. W1 was the richest in kaempferol 3-sophoroside (30.34 mg/g dry FB) and delphinidin 3,5-diglucoside (15.98 mg/g dry FB). The highest tested concentration (900 μg/ml) of W1, W2, E4, D5 and H6 did not significantly decrease the cell viability. Only E3 at that concentration caused a significant decrease of 38% in the cell viability. Therefore, all extracts studied are not cytotoxic at concentrations lower than 900 μg/ml, and W1 is proposed as the optimal for food applications due to its greater contribution of phenolic compounds.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Food Chemistry - Volume 147, 15 March 2014, Pages 55-59
Journal: Food Chemistry - Volume 147, 15 March 2014, Pages 55-59
نویسندگان
Jéssica Serrano-DÃaz, Carmen Estevan, M. Ángel Sogorb, Manuel Carmona, Gonzalo L. Alonso, Eugenio Vilanova,