کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7599638 1492144 2014 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Cytotoxic effect against 3T3 fibroblasts cells of saffron floral bio-residues extracts
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Cytotoxic effect against 3T3 fibroblasts cells of saffron floral bio-residues extracts
چکیده انگلیسی
For every kilogram of saffron spice produced, about 63 kg of floral bio-residues (FB) (tepals, stamens and styles) are thrown away. Extracts of these bio-residues in water (W1), water:HCl (100:1, v/v) (W2), ethanol (E3), ethanol:HCl (100:1, v/v) (E4), dichloromethane (D5) and hexane (H6) were prepared. Their composition in flavonols and anthocyanins, and their effect on cell viability were determined. W1 was the richest in kaempferol 3-sophoroside (30.34 mg/g dry FB) and delphinidin 3,5-diglucoside (15.98 mg/g dry FB). The highest tested concentration (900 μg/ml) of W1, W2, E4, D5 and H6 did not significantly decrease the cell viability. Only E3 at that concentration caused a significant decrease of 38% in the cell viability. Therefore, all extracts studied are not cytotoxic at concentrations lower than 900 μg/ml, and W1 is proposed as the optimal for food applications due to its greater contribution of phenolic compounds.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Food Chemistry - Volume 147, 15 March 2014, Pages 55-59
نویسندگان
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