کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7608541 | 1493383 | 2018 | 23 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Determination of free formaldehyde in cosmetics containing formaldehyde-releasing preservatives by reversed-phase dispersive liquid-liquid microextraction and liquid chromatography with post-column derivatization
ترجمه فارسی عنوان
تعیین فرمالدئید آزاد در لوازم آرایشی حاوی مواد نگهدارنده آزاد کننده فرمالدئید با استفاده از مایکروکساکسایزر مایع و مایع کروماتوگرافی مایع با ستون سازی پس از ستون
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
محصولات زیبایی، فرمالدئید، نگهدارنده های آزاد کننده فرمالدئید، کروماتوگرافی مایع مایکروسافت مایع معکوس فاز معکوس،
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی
An analytical method for the determination of traces of formaldehyde in cosmetic products containing formaldehyde-releasing preservatives has been developed. The method is based on reversed-phase dispersive liquid-liquid microextraction (RP-DLLME), that allows the extraction of highly polar compounds, followed by liquid chromatography-ultraviolet/visible (LC-UV/vis) determination with post-column derivatization. The variables involved in the RP-DLLME process were studied to provide the best enrichment factors. Under the selected conditions, a mixture of 500â¯Î¼L of acetonitrile (disperser solvent) and 50â¯Î¼L of water (extraction solvent) was rapidly injected into 5â¯mL of toluene sample solution. The extracts were injected into the LC-UV/vis system using phosphate buffer 6â¯mmolâ¯Lâ1 at pH 2 as mobile phase. After chromatographic separation, the eluate merged with a flow stream of pentane-2,4-dione in ammonium acetate solution as derivatizing reagent and passed throughout a post-column reactor at 85â¯Â°C in order to derivatize formaldehyde into 3,5-diacetyl-1,4-dihydrolutidine, according to Hantzsch reaction, which was finally measured spectrophotometrically at 407â¯nm. The method was successfully validated showing good linearity, an enrichment factor of 86â¯Â±â¯2, limits of detection and quantification of 0.7 and 2.3â¯ngâ¯mLâ1, respectively, and good repeatability (RSDâ¯<â¯9.2%). Finally, the proposed analytical method was applied to the determination of formaldehyde in different commercial cosmetic samples containing formaldehyde-releasing preservatives, such as bronopol, diazolidinyl urea, imidazolidinyl urea, and DMDM hydantoin, with good relative recovery values (91-113%) thus showing that matrix effects were negligible. The good analytical features of the proposed method besides of its simplicity and affordability, make it useful to carry out the quality control of cosmetic products containing formaldehyde-releasing preservatives.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Chromatography A - Volume 1543, 30 March 2018, Pages 34-39
Journal: Journal of Chromatography A - Volume 1543, 30 March 2018, Pages 34-39
نویسندگان
Pablo Miralles, Alberto Chisvert, M. José Alonso, Sandra Hernandorena, Amparo Salvador,