Ionic liquids as novel stationary phases in gas liquid chromatography: Inverse or normal isotope effect?

► Quantitative GC via SIDA: lower bleed of IL columns may benefit non-MS detection. ► Chromatographic separation of isotopic standard necessary for reliable integration. ► The isotope effect on polar ionic liquids is other than on apolar silicone phases. ► Discussion on theoretical background for observed difference of the isotope effect.