Highly sensitive trivalent copper chelate-luminol chemiluminescence system for capillary electrophoresis detection of epinephrine in the urine of smoker

► DPC was synthesized and used to develop a highly sensitive CL detection system. ► A CE-CL method was established for highly sensitive assay of EP in biological sample. ► Using this CE-CL method, smoking was found to stimulate the release of EP.