A new, rapid, stability-indicating UPLC method for separation and determination of impurities in amlodipine besylate, valsartan and hydrochlorothiazide in their combined tablet dosage form

- The UPLC method for separation of HCTZ, AMLO, VALS and their impurities is described.
- The sample preparation procedure from the combined tablets was developed.
- The forced degradation study was performed.
- The method was validated and could be used as a routine purity testing method.