Comparative metabolomics analysis on invigorating blood circulation for herb pair Gui-Hong by ultra-high-performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry and pattern recognition approach

- Comprehensive metabolomics approach by UHPLC-QTOF/MS and pattern recognition methods.
- Invigorate the circulation function of herb pair Gui-Hong.
- Fourteen endogenous metabolites were tentatively identified and 16 metabolic pathways were found.
- Danggui and Honghua can synergistically invigorate blood circulation.