Simplified LC-MS/MS method enabling the determination of azithromycin in human plasma after a low 100Â mg dose administration

- Azithromycin determination in human plasma in range of 0.5-250.0 ng/mL.
- First report of descladinose azithromycin back-conversion to the parent drug.
- Over 5000 plasma samples analysed using a single analytical column.
- Reduced organic solvent consumption and short extraction time.
- Fully validated method was successfully applied to a pharmacokinetic study.