Simultaneous determination of rivaroxaban and dabigatran levels in human plasma by high-performance liquid chromatography-tandem mass spectrometry

- Dabigatran and rivaroxaban are target specific oral anticoagulants (TSOACs).
- This is an analytical method to quantify simultaneously dabigatran and rivaroxaban in human plasma.
- Dabigatran and rivaroxaban are stable in plasma 1 month at 3 different conditions of temperature.
- It was successfully applied to 65 patient plasma samples.