LC-MS/MS quantitative analysis of paclitaxel and its major metabolites in serum, plasma and tissue from women with ovarian cancer after intraperitoneal chemotherapy

- A method for paclitaxel and its metabolites in serum and peritoneal tissue is reported.
- The method is based on LC-ESI-MS/MS in SRM mode.
- Serum and peritoneal tissue from women with ovarian cancer were the samples.
- Plasma can also been used as sample.