کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7631489 1494650 2013 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Application of an innovative design space optimization strategy to the development of LC methods for the simultaneous screening of antibiotics to combat poor quality medicines
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Application of an innovative design space optimization strategy to the development of LC methods for the simultaneous screening of antibiotics to combat poor quality medicines
چکیده انگلیسی

- Innovative design space methodology to develop generic and specific HPLC methods.
- Involvement of 19 molecules of pharmaceutical interest mainly targeted by counterfeit.
- Evaluation of the robustness of the predicted DS through geometric transfer while providing fast methods of analysis.
- Validation of the UHPLC method using the accuracy profile as decision tool.
- Confirmation of the poor quality of medicines phenomenon through quantification of real samples.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Pharmaceutical and Biomedical Analysis - Volume 85, November 2013, Pages 83-92
نویسندگان
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