Ternary system of dihydroartemisinin with hydroxypropyl-β-cyclodextrin and lecithin: Simultaneous enhancement of drug solubility and stability in aqueous solutions

- Formation of DHA-HP-β-CD-lecithin ternary system was confirmed by FT-IR, DSC and PXRD.
- Solubility and stability enhancements based on the formation of ternary system were verified.
- The possible molecular mechanism and structure of ternary system were proposed based on docking studies.
- The importance of hydrogen bonding and hydrophobic interaction for ternary system was discussed.