کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7631802 1494652 2013 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Ternary system of dihydroartemisinin with hydroxypropyl-β-cyclodextrin and lecithin: Simultaneous enhancement of drug solubility and stability in aqueous solutions
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Ternary system of dihydroartemisinin with hydroxypropyl-β-cyclodextrin and lecithin: Simultaneous enhancement of drug solubility and stability in aqueous solutions
چکیده انگلیسی

- Formation of DHA-HP-β-CD-lecithin ternary system was confirmed by FT-IR, DSC and PXRD.
- Solubility and stability enhancements based on the formation of ternary system were verified.
- The possible molecular mechanism and structure of ternary system were proposed based on docking studies.
- The importance of hydrogen bonding and hydrophobic interaction for ternary system was discussed.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Pharmaceutical and Biomedical Analysis - Volume 83, September 2013, Pages 141-148
نویسندگان
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