Determination of colistin A and colistin B in human plasma by UPLC-ESI high resolution tandem MS: Application to a pharmacokinetic study

- Determination of CS and CMS in human plasma by a new UPLC-ESI HR MS/MS method.
- The first UPLC-ESI HRMS/MS method for the quantitation of CSA and CSB.
- Excellent specificity, rapid analysis time and baseline separation of CSA/CSB.
- An ideal high-throughput method for the pharmacokinetic study of the drug.