A novel strategy for synthesis of hollow gold nanosphere and its application in electrogenerated chemiluminescence glucose biosensor

Hollow gold nanospheres (Aushell@GOD) have been synthesized with the method of using GOD cross-linked glutaraldehyde as template. A glucose biosensor was prepared based on the Aushell@GOD nanoparticles and electrogenerated chemiluminescence (ECL) technology. Results showed that, the obtained Aushell@GOD nanoparticles exhibited excellent catalytic effect towards the ECL of luminol-H2O2 system.