Determination of total leachable bisphenol A from polysulfone membranes based on multiple consecutive extractions

► We identified components in medical devices with high risk of BPA exposure. ► We developed an extraction method for accurate determination of total leachable BPA. ► We determined the total amount of BPA leachable in polysulfone hollow fibers. ► We derived a general equation for multiple consecutive partitions of leachables. ► We found repeated extractions give more accurate results than a single extraction.