Characterization of interactions between organotin compounds and human serum albumin by capillary electrophoresis coupled with inductively coupled plasma mass spectrometry

► Kb of organotin-HSA complexes were determined by ACE-ICP-MS and NECEEM-ICP-MS. ► Log Kb values between organotin compounds and HSA were in the range of 5.68-6.13. ► The interactions between tin compounds and HSA were non-covalent and reversible.