Utilization of inverted dispersive liquid-liquid microextraction followed by HPLC-UV as a sensitive and efficient method for the extraction and determination of quercetin in honey and biological samples

► IDLLME coupled with HPLC-UV has been developed for rapid determination of quercetin. ► Regard to SPE methods, lower LOD and wider linear range were obtained. ► Good recovery, high preconcentration factor and good reproducibility were achieved. ► In IDLLME, protein precipitation step before the extraction process is eliminated.