Application of low-temperature CP-Sil 88 column for the isomeric analysis of toxic 2378-substituted PCDD/Fs in incinerator flyash and sewage sludge using a triple quadrupole GC-MS/MS

► Toxic 2378-substituted PCDD/Fs were analyzed on a low temperature CP-Sil 88 column. ► Excellent chromatographic separation of the PCDD/Fs was achieved with a GC-MS/MS. ► Analytical procedure used for flyash and sewage sludge samples was fit-for-purpose. ► Reference flyash and sewage sludge gave deviations of 4.93% and 0.53%, respectively. ► Over an 18-month period, no significant loss of column performance was observed.