Multi-residue method for the determination of brominated and organophosphate flame retardants in indoor dust

► Simultaneous determination of multiple classes of flame retardants in dust. ► Simple and efficient extraction based on sonication and vortex. ► Two stage clean-up and fractionation based on silica and Florisil. ► GC/MS and LC/MS were employed for the analysis. ► The method is suitable to estimate human exposure via dust ingestion.