کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7687636 | 1495864 | 2018 | 36 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Recent progress in optical and electrochemical biosensors for sensing of Clostridium botulinum neurotoxin
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Botulinum toxin is a neurotoxic protein which produced from Clostridium botulinum and related species and it block acetylcholine release from presynaptic nerve terminals at the neuromuscular junctions. This toxin is life threatening for millions of people and growing menace to society since causing human botulism. Enzymatic activity of Botulinum neurotoxin within the cell made it hazardous and lead to flaccid paralysis. However, there isn't any reliable and precise remedy for this toxin. Therefore, there is an urgent need for early detection of this toxin in a fast and meticulous way with a robust and cost-effective relationship for real-time monitoring of Botulinum neurotoxin. Several biosensors have been designed and commercialized for this purpose. In this overview, novel biosensing methods; such as various optical and electrochemical ones proposed for detection of Botulinum neurotoxin have been summarized. Furthermore, attention has been focused on the main concepts, applications, and examples that have been achieved up to diagnostics of botulism.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: TrAC Trends in Analytical Chemistry - Volume 103, June 2018, Pages 184-197
Journal: TrAC Trends in Analytical Chemistry - Volume 103, June 2018, Pages 184-197
نویسندگان
Reza Eivazzadeh-Keihan, Paria Pashazadeh-Panahi, Behzad Baradaran, Miguel de la Guardia, Maryam Hejazi, Hessamaddin Sohrabi, Ahad Mokhtarzadeh, Ali Maleki,