Current and future trends in UHPLC

- Ultra-high-performance liquid chromatography UHPLC is the standard LC platform.
- Columns packed with sub-2µm particles come for chiral-LC, SEC, IEX, HILIC and SFC.
- Detailed characterization of biopharmaceuticals is an important UHPLC application.
- Particle-size reduction and system-pressure increase are technologically difficult.
- Superficially porous particles directly improve the kinetic performance of UHPLC.