Nickel(II) bis(isatin thiosemicarbazone) complexes induced apoptosis through mitochondrial signaling pathway and G0/G1 cell cycle arrest in IM-9 cells

Isatin thiosemicarbazone based nickel(II) complex 4 showed promising anticancer activity, and induced morphological changes, apoptosis, cell cycle arrest at G1 phase in IM-9 cells.119