Cytotoxicity of Ru(II) piano-stool complexes with chloroquine and chelating ligands against breast and lung tumor cells: Interactions with DNA and BSA

Piano-stool type complexes of the formulae [RuX(η6-C10H14)(N-N)] were synthesized and fully characterized. All compounds exerted some degree of growth inhibition on human tumor cell lines and their affinity to BSA, interaction with DNA and lipophilic properties was mainly responsible for the observed activity.277