کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7783548 | 1500572 | 2018 | 45 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Nanostructured electrospun nonwovens of poly(ε-caprolactone)/quaternized chitosan for potential biomedical applications
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Blend solutions of poly(ε-caprolactone) (PCL) and N-(2-hydroxy)-propyl-3-trimethylammonium chitosan chloride (QCh) were successfully electrospun. The weight ratio PCL/QCh ranged in the interval 95/5-70/30 while two QCh samples were used, namely QCh1 (DQ¯â¯=â¯47.3%; DPv¯â¯=â¯2218) and QCh2 (DQ¯â¯=â¯71.1%; DPv¯â¯=â¯1427). According to the characteristics of QCh derivative and to the QCh content on the resulting PCL/QCh nonwoven, the nanofibers displayed different average diameter (175â¯nm-415â¯nm), and the nonwovens exhibited variable porosity (57.0%-81.6%), swelling capacity (175%-425%) and water vapor transmission rate (1600â¯gâ¯mâ2 24â¯h-2500â¯gâ¯mâ2 24â¯h). The surface hydrophilicity of nonwovens increases with increasing QCh content, favoring fibroblast (HDFn) adhesion and spreading. Tensile tests revealed that the nonwovens present a good balance between elasticity and strength under both dry and hydrated state. Results indicate that the PCL/QCh electrospun nonwovens are new nanofibers-based biomaterials potentially useful as wound dressings.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Polymers - Volume 186, 15 April 2018, Pages 110-121
Journal: Carbohydrate Polymers - Volume 186, 15 April 2018, Pages 110-121
نویسندگان
Danilo Martins dos Santos, Ilaiáli Souza Leite, Andrea de Lacerda Bukzem, Rachel Passos de Oliveira Santos, Elisabete Frollini, Natalia Mayumi Inada, Sérgio Paulo Campana-Filho,