کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7786593 | 1500622 | 2016 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Optimization of selenylation modification for garlic polysaccharide based on immune-enhancing activity
ترجمه فارسی عنوان
بهینه سازی اصلاح سلنیلیت سازی برای پلی ساکارید سیر بر اساس فعالیت تقویت ایمنی
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کلمات کلیدی
Sodium selenite (PubChem CID: 24934)Perchloric acid (PubChem CID: 24247)Glacial acetic acid (Pubchem CID: 176)Selenylation modificationAscorbic acid (PubChem CID: 54670067) - اسید اسکوربیک (PubChem CID: 54670067)Nitric acid (PubChem CID: 944) - اسید نیتریک (PubChem CID: 944)Hydrochloric acid (PubChem CID: 313) - اسید هیدروکلریک (PubChem CID: 313)Lymphocyte proliferation - تکثیر لنفوسیتGPS - سامانه موقعیتیاب جهانیCytokines - سیتوکین هاSOC - سیستم روی یک تراشهImmune response - پاسخ یا واکنش ایمنیPyridine (PubChem CID: 1049) - پیریدین (PubChem CID: 1049)
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
چکیده انگلیسی
Garlic polysaccharide (GPS) was modified in selenylation respectively by nitric acid-sodium selenite (NA-SS), glacial acetic acid-selenous acid (GA-SA), glacial acetic acid-sodium selenite (GA-SS) and selenium oxychloride (SOC) methods each under nine modification conditions of L9(34) orthogonal design and each to obtain nine selenizing GPSs (sGPSs). Their structures were identified, yields and selenium contents were determined, selenium yields were calculated, and the immune-enhancing activities of four sGPSs with higher selenium yields were compared taking unmodified GPS as control. The results showed that among four methods the selenylation efficiency of NA-SS method were the highest, the activity of sGPS5 was the strongest and significantly stronger than that of unmodified GPS. This indicates that selenylation modification can significantly enhance the immune-enhancing activity of GPS, NA-SS method is the best method and the optimal conditions are 0.8:1 weight ratio of sodium selenite to GPS, reaction temperature of 70 °C and reaction time of 10 h.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Polymers - Volume 136, 20 January 2016, Pages 560-569
Journal: Carbohydrate Polymers - Volume 136, 20 January 2016, Pages 560-569
نویسندگان
Zhenzhen Gao, Jin Chen, Shulei Qiu, Youying Li, Deyun Wang, Cui Liu, Xiuping Li, Ranran Hou, Chanjuan Yue, Jie Liu, Hongquan Li, Yuanliang Hu,