کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7787816 | 1500625 | 2015 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
(1â6)- and (1â3)(1â6)-β-glucans from Lasiodiplodia theobromae MMBJ: Structural characterization and pro-inflammatory activity
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: (1â6)- and (1â3)(1â6)-β-glucans from Lasiodiplodia theobromae MMBJ: Structural characterization and pro-inflammatory activity (1â6)- and (1â3)(1â6)-β-glucans from Lasiodiplodia theobromae MMBJ: Structural characterization and pro-inflammatory activity](/preview/png/7787816.png)
چکیده انگلیسی
The chemical composition and structural characterization of exopolysaccharides from the fungus Lasiodiplodia theobromae MMBJ are described, and the immunomodulatory activity of a purified β-glucan was evaluated. L. theobromae MMBJ produced three different β-glucans. One, fraction PEPS, was a branched (1â3)(1â6)-β-glucan and was insoluble in cold water. The other two, fractions SEPS-005R and SEPS-10E, were characterized as linear (1â6)-β-glucans with molar mass of 1.8 Ã 106 Da and 7.0 Ã 103 Da, respectively. From a total of 2.2 g/L of EPS produced by L. theobromae through submerged fermentation, 1.5 g/L (67%) was of the branched (1â3)(1â6)-β-glucan, while 25% (w/w) were linear (1â6)-β-glucans. Tests conducted with macrophages showed that the high molar mass (1â6)-β-glucan fraction (SEPS-005R) induced a pro-inflammatory response pattern.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Polymers - Volume 133, 20 November 2015, Pages 539-546
Journal: Carbohydrate Polymers - Volume 133, 20 November 2015, Pages 539-546
نویسندگان
Kassandra S.M. Oliveira, Mirela Di Bastiani, Lucimara M.C. Cordeiro, MÃrian F. Costa, Karina A. Toledo, Marcello Iacomini, Aneli M. Babosa, Robert F.H. Dekker, Valéria M.G. Nascimento,