کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7842051 | 1506506 | 2018 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Features of interaction of tetraiodide meso-tetra(N-methyl-3-pyridyl)porphyrin with bovine serum albumin
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی تئوریک و عملی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
The interaction processes spectral study of tetraiodide meso-tetra(N-methyl-3-pyridyl)porphyrin with blood serum albumin has been carried out. The results obtained are considered in comparison with similar data for tetraphenylporphyrin and tetraiodide meso-tetra(N-methyl-4-pyridyl)porphyrin. It is established that interaction of albumin with the porphyrins under study leads to a change in the secondary structure of the protein accompanied by a decrease in the proportion of disordered fragments of the protein and an increase in β-structuring within the complexes. NCH3+ group isomerism position in the porphyrin compound significantly affects binding to albumin. Adding of the substituent in meta-position of the phenyl ring contributes to the increased affinity of protein to the cationic porphyrin, compared to the pair-substituted counterpart.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Molecular Liquids - Volume 265, 1 September 2018, Pages 664-667
Journal: Journal of Molecular Liquids - Volume 265, 1 September 2018, Pages 664-667
نویسندگان
Natalia Sh. Lebedeva, Yury A. Gubarev, Elena S. Yurina, Sergey A. Syrbu,