Evaluation of the effects of chemically different linkers on hepatic accumulations, cell tropism and gene silencing ability of cholesterol-conjugated antisense oligonucleotides

Evaluation of the effects of chemically different linkers on hepatic accumulations, cell tropism and gene silencing ability of cholesterol-conjugated antisense oligonucleotides

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Controlled Release - Volume 226, 28 March 2016, Pages 57-65

Shunsuke Wada, Hidenori Yasuhara, Fumito Wada, Motoki Sawamura, Reiko Waki, Tsuyoshi Yamamoto, Mariko Harada-Shiba, Satoshi Obika,