کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7868791 | 1509162 | 2016 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Processing and characterization of diatom nanoparticles and microparticles as potential source of silicon for bone tissue engineering
ترجمه فارسی عنوان
پردازش و مشخص کردن نانوذرات دیاتومتری و میکروکاستیک به عنوان منبع بالقوه سیلیکون برای مهندسی بافت استخوان
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کلمات کلیدی
DLSICPSAEDTem - این استBone regeneration - بازسازی استخوانEnergy dispersive X-ray analysis - تجزیه و تحلیل اشعه ایکس پراکنده انرژیDiatomite - دیاتومیتSilica - سیلیس یا سیلیکاCAD - طراحی به کمک رایانه یا کَدX-ray photoelectron spectroscopy - طیف سنجی فوتوالکتر اشعه ایکسXPS - طیف نگاری فوتوالکترونی اشعه ایکسSEM - مدل معادلات ساختاری / میکروسکوپ الکترونی روبشیScanning electron microscopy - میکروسکوپ الکترونی روبشیTransmission electron microscopy - میکروسکوپ الکترونی عبوریEDAX - پر خورDynamic Light Scattering - پراکندگی نور دینامیکیinductively coupled plasma - پلاسما جفتشده القایی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی مواد
بیومتریال
چکیده انگلیسی
Silicon plays an important role in bone formation and maintenance, improving osteoblast cell function and inducing mineralization. Often, bone deformation and long bone abnormalities have been associated with silica/silicon deficiency. Diatomite, a natural deposit of diatom skeleton, is a cheap and abundant source of biogenic silica. The aim of the present study is to validate the potential of diatom particles derived from diatom skeletons as silicon-donor materials for bone tissue engineering applications. Raw diatomite (RD) and calcined diatomite (CD) powders were purified by acid treatments, and diatom microparticles (MPs) and nanoparticles (NPs) were produced by fragmentation of purified diatoms under alkaline conditions. The influence of processing on the surface chemical composition of purified diatomites was evaluated by X-ray photoelectron spectroscopy (XPS). Diatoms NPs were also characterized in terms of morphology and size distribution by transmission electron microscopy (TEM) and Dynamic light scattering (DLS), while diatom MPs morphology was analyzed by scanning electron microscopy (SEM). Surface area and microporosity of the diatom particles were evaluated by nitrogen physisorption methods. Release of silicon ions from diatom-derived particles was demonstrated using inductively coupled plasma optical emission spectrometry (ICP/OES); furthermore, silicon release kinetic was found to be influenced by diatomite purification method and particle size. Diatom-derived microparticles (MPs) and nanoparticles (NPs) showed limited or no cytotoxic effect in vitro depending on the administration conditions.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Materials Science and Engineering: C - Volume 59, 1 February 2016, Pages 471-479
Journal: Materials Science and Engineering: C - Volume 59, 1 February 2016, Pages 471-479
نویسندگان
Thi Duy Hanh Le, Walter Bonani, Giorgio Speranza, Vincenzo Sglavo, Riccardo Ceccato, Devid Maniglio, Antonella Motta, Claudio Migliaresi,