Maximum reasonable radioxenon releases from medical isotope production facilities and their effect on monitoring nuclear explosions

► Effluents from production of medical isotopes can interfere with detection of nuclear explosions. ► The International Monitoring System detects radioactive xenon isotopes at many stations. ► Acceptable emissions levels need to be calculated to guide current and future production. ► A maximum release of 5 × 109 Bq/day 133Xe will have minimal impact on monitoring.