کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8248444 | 1533343 | 2018 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Performance evaluation of the LightPath imaging system for intra-operative Cerenkov luminescence imaging
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
فیزیک و نجوم
تشعشع
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
The performances of an intra-operative optical imaging system for Cerenkov luminescence imaging of resected tumor specimens were evaluated with phantom studies. The spatial resolution, the linearity of the measured signal with the activity concentration and the minimum detectable activity concentration were considered. A high linearity was observed over a broad range of activity concentration (R2⩾0.99 down to â¼40â¯kBq/ml of 18F-FDG). For 18F-FDG activity distributions 2â¯mm deep in biological tissue, the measured detection limit was 8â¯kBq/ml and a spatial resolution of 2.5â¯mm was obtained. The detection limit of the imaging system is comparable with clinical activity concentrations in tumor specimens, and the spatial resolution is compatible with clinical requirements.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Physica Medica - Volume 52, August 2018, Pages 122-128
Journal: Physica Medica - Volume 52, August 2018, Pages 122-128
نویسندگان
Esther Ciarrocchi, Christian Vanhove, Benedicte Descamps, Stef De Lombaerde, Stefaan Vandenberghe, Nicola Belcari,