Urinary monocyte chemoattractant protein-1 in renal disease

► MCP-1 is a chemokine for macrophage and T cells. ► Increased MCP-1 in renal tissue and urine in renal diseases. ► Including glomerulonephritis, diabetic nephropathy, renal allograft rejection. ► Prognostic of long term clinical outcome. ► A potential therapeutic target.