Diagnostic utility of a single-epitope sandwich B-type natriuretic peptide assay in stable coronary artery disease: Data from the Akershus Cardiac Examination (ACE) 1 Study

► The single-epitope sandwich (SES) assay is specific to the ring structure of BNP. ► BNP levels are increased in patients with reversible myocardial ischemia. ► Measuring BNP after stress testing does not improve diagnostic accuracy. ► The SES-BNP assay was associated with ischemia by several statistical indices. ► A conventional BNP assay was not associated with ischemia in multivariate analyses.