Acetylcholine and antibodies against the acetylcholine receptor protect neurons and astrocytes against beta-amyloid toxicity

► Antibodies to α7 acetylcholine receptors protect against Aβ-induced cell death. ► Acetylcholine and AchRabs significantly reduce Aβ-induced ROS production. ► Acetylcholine pathway modulates the activity of the NADPH oxidase. ► Acetylcholine and AchRabs do not affect the Aβ-induced Ca2+-signal.