کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8335406 1540277 2012 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Investigation of the inclusion behavior of chlorogenic acid with hydroxypropyl-β-cyclodextrin
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Investigation of the inclusion behavior of chlorogenic acid with hydroxypropyl-β-cyclodextrin
چکیده انگلیسی
The inclusion complexation behavior of chlorogenic acid (CGA) with the hydroxypropyl-β-cyclodextrin (HP-β-CD) was investigated in both solution and the solid state by UV-vis and fluorescence spectroscopy, infrared spectroscopy (IR), NMR spectroscopy as well as differential scanning calorimetry (DSC). The experimental results indicate that CGA is able to form an inclusion complex with HP-β-CD. The inclusion complex has a stoichiometry of 1:1 and the formation constant was calculated to be 155.7 M−1. The antioxidant activity of CGA on complexation with HP-β-CD increased as compared to uncomplexed CGA. NMR spectroscopic studies show that the aromatic ring and the vinyl group of CGA are deeply included inside the CD cavity.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Biological Macromolecules - Volume 50, Issue 1, 1 January 2012, Pages 277-282
نویسندگان
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