The role of enoyl reductase genes in phloridzin biosynthesis in apple

► Six apple enoyl-CoA reductase genes were screened for their role in phloridzin biosynthesis. ► ENRL-3 gave a significant increase in phloridzin production in transient assays. ► ENRL-5 reduced p-coumaroyl CoA in biochemical assays. ► One ENRL-3 silenced apple line yielded a 67% decrease in phloridzin concentration