Blue light-emitting diode light at 405 and 465 nm can inhibit a Miamiensis avidus infection in olive flounder, Paralichthys olivaceus

This is the first study to demonstrate that blue LED light irradiation can inhibit a parasitic pathogen, Miamiensis avidus, by inducing apoptosis. Also, photoinactivation by 405 and 465 nm LED can reduce mortality of live flounder due to scuticociliatosis using in vivo experiments without causing any severe side effects or inducing stress responses. Data obtained in this study indicate that such light therapy may have tremendous benefit, although further research is needed before applying such therapy for intensive fish farming and commercial aquarium facility in the future.