FRET peptides reveal differential proteolytic activation in intraerythrocytic stages of the malaria parasites Plasmodium berghei and Plasmodium yoelii

► Ex vivo protease activation measurements in malaria parasites using FRET peptides. ► Calcium modulation in protease activation differs within the rodent malaria parasites, Plasmodium berghei and Plasmodium yoelii. ► Differences in the protease activity profile during intraerythrocytic stages of P. berghei and P. yoelli.