Preparation of poly(lactide-co-glycolide) microspheres and evaluation of pharmacokinetics and tissue distribution of BDMC-PLGA-MS in rats

Poly (lactic-co-glycolic acid) (PLGA)-based microspheres formulation of Bisdemethoxycurcum (BDMC) was prepared by emulsion-solvent evaporation method. The pharmacokinetics and tissue distribution in rats were conducted to evaluate BDMC-PLGA-MS preliminarily.