کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8522299 | 1557752 | 2018 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
GC quantitative analysis of benzyl isothiocyanate in Salvadora persica roots extract and dental care herbal products
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
داروسازی، سم شناسی و علوم دارویی
علوم دارویی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
An accurate, sensitive, precise and simple method was developed utilizing Gas Chromatography for the quantitative analysis of benzyl isothicyanate in Siwak extract and dental care herbal products claimed to contain Siwak. Rtx (30.0â¯mâ¯Ãâ¯0.25â¯mm ID, 25â¯Âµm thickness) column was used and helium as carrier gas at a flow rate of 0.74â¯mL/min. The retention time of standard benzyl isothicyanate was 13.470â¯min under the described conditions. Linear regression data analysis indicated a good linear relationship between peak height measurement and concentration of benzyl isothiocyanate in the range of 10-50â¯Âµg/ml (R2â¯=â¯0.9971). The regression equation was yâ¯=â¯11,471x. The developed GC method was subjected to validation requirements set by the ICH for precision, accuracy, and robustness. The entitled GC analyses expected to be valuable for the determination of benzyl isothiocyanate in Siwak extracts and other formulations containing Siwak extract. The amount of benzyl isothiocyanate reflects the efficacy of the products.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Saudi Pharmaceutical Journal - Volume 26, Issue 4, May 2018, Pages 462-466
Journal: Saudi Pharmaceutical Journal - Volume 26, Issue 4, May 2018, Pages 462-466
نویسندگان
Maged Saad Abdel-Kader, Elsadig Hassan Khamis, Ahmed Ibrahim Foudah, Mohammed Hamed Alqarni,